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BlueGnome Limited microarray-based cgh array analysis
Microarray Based Cgh Array Analysis, supplied by BlueGnome Limited, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/cgh-array+analysis/array+cgh/pmc04150148-137-64-6
Average 90 stars, based on 1 article reviews
microarray-based cgh array analysis - by Bioz Stars, 2026-11
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Article Title: Polar body analysis by array comparative genomic hybridization accurately predicts aneuploidies of maternal meiotic origin in cleavage stage embryos of women of advanced maternal age.
Article Snippet: Whole genome amplification and array CGH analysis Whole genome amplification (SurePlex; BlueGnome, Cambridge, UK) and array CGH (24sure V2 and 24sure+; BlueGnome, Cambridge, UK) analysis of polar bodies and cleavage stage embryos was carried out according to the manufacturer’s instructions.

Article Title: OMICS: Current and future perspectives in reproductive medicine and technology
Article Snippet: As an example, the Cambridge-based company BlueGnome offers an array-based CGH protocol which allows analysis of biopsied polar body (PBs) within 11 h.[ ] A proof-of-principle study was carried out by Geraedts et al .[ ] and Magli et al .[ ] to determine the reliability of an alternative form of PGS, i.e., PGS by PB biopsy, with whole genome amplification (WGA) and microarray-based CGH array analysis.

Article Title: XCI-escaping gene KDM5C contributes to ovarian development via downregulating miR-320a.
Article Snippet: XCI-escaping gene KDM5C in PBMCs.. In vitro models indicated that KDM5C suppressed miR-320a transcription by directly binding to the promoter of miR-320a to prevent histone methylation.. In addition, we demonstrated that KITLG, an essential gene for ovarian development and primordial germ cell survival, was a direct target of miR-320a and that it was downregulated in 45,X fetal gonadal tissues.

Article Title: Xq21.1q21.31 Duplication in Two Male Siblings
Article Snippet: Array CGH analysis of the proband and his brother was performed using the BlueGnome 8 × 60K v2.0 ISCA platform, with probes mapped to the GRCh37 (hg19) human genome assembly.

Article Title: A novel MED12 mutation: Evidence for a fourth phenotype.
Article Snippet: A Novel MED12 Mutation: Evidence for a Fourth Phenotype Paolo Prontera,* Valentina Ottaviani, Daniela Rogaia, Ilenia Isidori, Amedea Mencarelli, Natascia Malerba, Dario Cocciadiferro, Pfundt Rolph, Gabriela Stangoni, Anneke Vulto-vanSilfhout, and Giuseppe Merla Medical Genetics Unit, Hospital “Santa Maria della Misericordia”, Perugia, Italy Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy Ph.D.. Program in Experimental and Regenerative Medicine, University of Foggia, Foggia, Italy Department of Human Genetics, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

Article Title: Morphological and Kinetic Embryological Criteria and Correlation with Aneuploidy Rates: How Might they Be Used to Choose the Best IVF Embryo for Transfer?
Article Snippet: Biopsied cells were sent to Reprogenetics laboratory LA, for analysis using array CGH (Bluegnome, Cambridge UK).

Article Title: 2q37.3 Deletion Syndrome: Two Cases with Highly Distinctive Facial Phenotype, Discordant Association with Schizophrenic Psychosis, and Shared Deletion Breakpoint Region on 2q37.3.
Article Snippet: Additional array-CGH analysis (CytoChip Oligo ISCA 4×180K; BlueGnome, Cambridge, UK) in case 1 revealed a karyotype arr 2q37.3(237,720,284– 242,951,149)×1 (Ensembl Release 64), thus confirming the breakpoint region at approximately 237.7 Mb ± 100 kb ( fig. 3 ).

Fluorescence In Situ Hybridization:

Article Title: Meeting abstracts from the 11th European Cytogenetics Conference
Article Snippet: .. Array CGH analysis on peripheral blood using BlueGnome CytoChip Oligo 8x60K array and FISH analysis on cultured lymphocytes with BAC probes (RP11) were performed. ..

Cell Culture:

Article Title: Meeting abstracts from the 11th European Cytogenetics Conference
Article Snippet: .. Array CGH analysis on peripheral blood using BlueGnome CytoChip Oligo 8x60K array and FISH analysis on cultured lymphocytes with BAC probes (RP11) were performed. ..

BAC Assay:

Article Title: Meeting abstracts from the 11th European Cytogenetics Conference
Article Snippet: .. Array CGH analysis on peripheral blood using BlueGnome CytoChip Oligo 8x60K array and FISH analysis on cultured lymphocytes with BAC probes (RP11) were performed. ..



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A) Result of <t>array-CGH</t> analysis of chromosome 2 <t>with</t> <t>Agilent</t> Human Genome CGH microarray Kit G3 400 in patient 1. The 1.914 Mb interstitial q37.1 deleted region of chromosome 2 extends between oligomers A_18_P13670199 (231,264,956 bp) and A_16_P00618306 (233,178,325 bp) flanked by oligomers A_16_P00615757 (231,257,468 bp) and A_16_P00618312 (233,181,399 bp) (UCSC Genome Browser, http://genome.ucsc.edu/ ; February 2009). B) FISH with BAC clones RP11-395A23 (AC010149) (chr2:231,304,236–231,476,367). The arrowhead indicates the deleted chromosome 2. D) Result of array-CGH analysis of chromosome 2 with Agilent Human Genome CGH microarray Kit G3 400 in patient 2. The 4.515 Mb interstitial deletion at bands q37.1q37.3 of chromosome 2 was comprised between oligomers A_16_P16076619 (232,963,736 bp) and A_16_P36124457(237,479,062 bp) flanked by oligomers A_16_P16076610 (232,954,321 bp) and A_16_P36124475 (237,483,914 bp). C) FISH with RP11-485M18 (AC079400)(chr2:236,766,818-236,919,215). The arrowhead shows the deleted chromosome 2.
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A) Result of <t>array-CGH</t> analysis of chromosome 2 <t>with</t> <t>Agilent</t> Human Genome CGH microarray Kit G3 400 in patient 1. The 1.914 Mb interstitial q37.1 deleted region of chromosome 2 extends between oligomers A_18_P13670199 (231,264,956 bp) and A_16_P00618306 (233,178,325 bp) flanked by oligomers A_16_P00615757 (231,257,468 bp) and A_16_P00618312 (233,181,399 bp) (UCSC Genome Browser, http://genome.ucsc.edu/ ; February 2009). B) FISH with BAC clones RP11-395A23 (AC010149) (chr2:231,304,236–231,476,367). The arrowhead indicates the deleted chromosome 2. D) Result of array-CGH analysis of chromosome 2 with Agilent Human Genome CGH microarray Kit G3 400 in patient 2. The 4.515 Mb interstitial deletion at bands q37.1q37.3 of chromosome 2 was comprised between oligomers A_16_P16076619 (232,963,736 bp) and A_16_P36124457(237,479,062 bp) flanked by oligomers A_16_P16076610 (232,954,321 bp) and A_16_P36124475 (237,483,914 bp). C) FISH with RP11-485M18 (AC079400)(chr2:236,766,818-236,919,215). The arrowhead shows the deleted chromosome 2.
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A) Result of array-CGH analysis of chromosome 2 with Agilent Human Genome CGH microarray Kit G3 400 in patient 1. The 1.914 Mb interstitial q37.1 deleted region of chromosome 2 extends between oligomers A_18_P13670199 (231,264,956 bp) and A_16_P00618306 (233,178,325 bp) flanked by oligomers A_16_P00615757 (231,257,468 bp) and A_16_P00618312 (233,181,399 bp) (UCSC Genome Browser, http://genome.ucsc.edu/ ; February 2009). B) FISH with BAC clones RP11-395A23 (AC010149) (chr2:231,304,236–231,476,367). The arrowhead indicates the deleted chromosome 2. D) Result of array-CGH analysis of chromosome 2 with Agilent Human Genome CGH microarray Kit G3 400 in patient 2. The 4.515 Mb interstitial deletion at bands q37.1q37.3 of chromosome 2 was comprised between oligomers A_16_P16076619 (232,963,736 bp) and A_16_P36124457(237,479,062 bp) flanked by oligomers A_16_P16076610 (232,954,321 bp) and A_16_P36124475 (237,483,914 bp). C) FISH with RP11-485M18 (AC079400)(chr2:236,766,818-236,919,215). The arrowhead shows the deleted chromosome 2.

Journal: PLoS ONE

Article Title: Genotype-Phenotype Correlation of 2q37 Deletions Including NPPC Gene Associated with Skeletal Malformations

doi: 10.1371/journal.pone.0066048

Figure Lengend Snippet: A) Result of array-CGH analysis of chromosome 2 with Agilent Human Genome CGH microarray Kit G3 400 in patient 1. The 1.914 Mb interstitial q37.1 deleted region of chromosome 2 extends between oligomers A_18_P13670199 (231,264,956 bp) and A_16_P00618306 (233,178,325 bp) flanked by oligomers A_16_P00615757 (231,257,468 bp) and A_16_P00618312 (233,181,399 bp) (UCSC Genome Browser, http://genome.ucsc.edu/ ; February 2009). B) FISH with BAC clones RP11-395A23 (AC010149) (chr2:231,304,236–231,476,367). The arrowhead indicates the deleted chromosome 2. D) Result of array-CGH analysis of chromosome 2 with Agilent Human Genome CGH microarray Kit G3 400 in patient 2. The 4.515 Mb interstitial deletion at bands q37.1q37.3 of chromosome 2 was comprised between oligomers A_16_P16076619 (232,963,736 bp) and A_16_P36124457(237,479,062 bp) flanked by oligomers A_16_P16076610 (232,954,321 bp) and A_16_P36124475 (237,483,914 bp). C) FISH with RP11-485M18 (AC079400)(chr2:236,766,818-236,919,215). The arrowhead shows the deleted chromosome 2.

Article Snippet: Considering the phenotypic abnormalities of the patients, array CGH analysis (Agilent G3 400 K) was performed.

Techniques: Microarray, Clone Assay